KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
31.21
Human Site:
T185
Identified Species:
57.22
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
T185
T
R
R
R
I
F
S
T
L
N
E
F
V
S
H
Chimpanzee
Pan troglodytes
XP_518702
505
58217
T185
T
R
R
R
I
F
S
T
L
N
E
F
V
S
H
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
T185
T
R
R
I
T
F
S
T
L
N
E
F
V
S
H
Dog
Lupus familis
XP_539091
505
57709
T189
S
Q
K
R
T
F
P
T
L
N
E
F
V
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
T192
T
R
R
K
V
F
S
T
L
N
E
F
V
N
Y
Rat
Rattus norvegicus
Q62662
506
58147
T186
T
R
R
K
T
F
S
T
L
N
E
F
V
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
R217
G
G
Y
Y
I
T
T
R
A
Q
F
D
T
I
Q
Frog
Xenopus laevis
P13406
537
60828
R218
G
G
Y
Y
I
T
T
R
A
Q
F
E
T
L
Q
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
K183
R
L
A
E
P
C
K
K
S
V
A
P
E
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
T199
A
R
R
T
T
F
R
T
L
Q
E
L
V
E
H
Honey Bee
Apis mellifera
XP_396043
451
51726
S158
E
S
R
H
N
D
Y
S
L
S
V
R
D
G
D
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
T193
A
R
R
R
P
F
A
T
L
H
D
L
I
A
H
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
T213
A
R
R
C
T
F
A
T
L
V
E
L
V
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
100
86.6
66.6
N.A.
73.3
73.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
53.3
13.3
46.6
53.3
P-Site Similarity:
100
100
86.6
86.6
N.A.
100
93.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
53.3
26.6
80
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
0
0
16
0
16
0
8
0
0
8
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
8
8
0
8
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
62
8
8
8
0
% E
% Phe:
0
0
0
0
0
70
0
0
0
0
16
47
0
0
0
% F
% Gly:
16
16
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
62
% H
% Ile:
0
0
0
8
31
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
16
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
77
0
0
24
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
47
0
0
0
16
0
% N
% Pro:
0
0
0
0
16
0
8
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
24
0
0
0
8
16
% Q
% Arg:
8
62
70
31
0
0
8
16
0
0
0
8
0
0
0
% R
% Ser:
8
8
0
0
0
0
39
8
8
8
0
0
0
31
0
% S
% Thr:
39
0
0
8
39
16
16
70
0
0
0
0
16
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
16
8
0
62
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
16
0
0
8
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _